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Sesquiterpene lactone
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Everything about Sesquiterpene Lactone totally explained

Sesquiterpene lactones are a class of chemical found in many plants that can cause allergic reactions. Some plants containing these compounds are:
Artemesinin, a new, highly-effective anti-malarial compound, is a sesquiterpene lactone found in Chinese wormwood. Lactucin, desoxylactucin, lactucopicrin, lactucin-15-oxalaat, lactucopicrin-15-oxalaat are some of the most prominent and well determinable sesquiterpene lactones found for example in lettuce and spinach, giving most of the bitter taste in these crops.

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